BOSTON (CBS) — One firefighter and four residents were injured in a fire at a multi-family home Tuesday afternoon, the Boston Fire Department said.

The fire chief said 21 people have been displaced as a result of the Havre Street blaze in East Boston.

READ MORE: Elijah Lewis Search: Large Police Presence In Abington Related To Missing 5-Year-Old Boy

At one point, smoke and flames could be seen coming out of the roof.

A mom and three children who inhaled smoke were taken to the hospital and a firefighter suffered minor burns.

A fire at an East Boston apartment building warrants a large response effort Tuesday (WBZ-TV)

Firefighters started working against the flames on the roof and from within the 3-story, 6-unit apartment building around 12:30 p.m.

READ MORE: MAP: Town-By-Town COVID Vaccination Rates For School-Aged Children

Within an hour they were called off the roof and third floor.

The fire department also said they were worried the chimney might collapse because the roof area around it has burned away.

Witnesses say the fire started on the third floor and spread up to the attic and down to the second floor.

Flames on the roof of a Harve Street building on Tuesday (Photo Courtesy: Boston Fire Department)

The fire was knocked down just after 2:30 p.m. Crews stayed on scene to watch for hot spots.

MORE NEWS: USS Constitution Fires 21-Gun Salute With Newly-Trailed Navy Sailors Aboard

It is not clear what started the fire, the department has not released any more information at this time.