BOSTON (CBS) — On Wednesday, the Second Circuit delivered a swift blow to Tom Brady’s hopes of playing all 16 games in 2016. And, as you might expect, his opponents aren’t exactly shedding a tear.

The Patriots play the Arizona Cardinals in Week 1, and Cardinals defensive end Calais Campbell was delighted by the news on Wednesday.

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“Oh yeah, licking my chops, man,” Campbell told Tiki & Tierney on CBS Sports Radio. “Rookie quarterback, pretty much. It’s always exciting when you get a guy like that for his first game, because he’s going to be nervous. He’s probably going to be sitting there, holding the ball a little longer or trying to get rid of it quick, throwing bad balls and stuff. So, as a vet we definitely pride ourselves on welcoming rookies the right way.”

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Garoppolo is, of course, not a rookie. This will be his third year in the NFL. But it will be his first start, and facing the Cardinals on national television in a game that matters will without a doubt be the biggest challenge of his young career.

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And it will also come with a healthy dose of bulletin-board material. Bill Belichick must be licking his chops to drop that tidbit on his “rookie” quarterback.