BOSTON (CBS) – The Red Sox and Rays conclude their series at Fenway Wednesday afternoon, with a little shuffle in the infield.

Kevin Youkilis will return after getting Tuesday’s nightcap off, but moves across the diamond to first base. Adrian Gonzalez will DH, replacing the ailing David Ortiz. Jed Lowrie will start his second straight game at third.

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John Lackey (11-8, 6.13 ERA) goes for his seventh win in his last eight starts. He has won six straight decisions since July 9th, the longest stretch of his career. He is opposed by the Rays David Price (10-10, 3.76 ERA), who is 5-3 with a 3.55 ERA in eight starts against Boston.

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The Sox are 27-12 this season in series finales.

Here is the full Red Sox lineup for Wednesday:

Jacoby Ellsbury, CF

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Dustin Pedroia, 2B

Adrian Gonzalez, DH

Kevin Youkilis, 1B

Jed Lowrie, 3B

Darnell McDonald, RF

Carl Crawford, LF

Jarrod Saltalamacchia, C

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Mike Aviles, SS