BOSTON (CBS) – Scientists in Massachusetts have made a potential breakthrough in ALS research.

In 1993, Dr. Robert Brown and his team at UMass discovered the first gene linked to familial ALS. His team, working with Massachusetts General Hospital, has now safely treated two people using synthetic microRNA for the first time. The microRNA suppressed and silenced the gene that caused ALS.

Dr. Robert Brown and his team have now safely treated two people using synthetic microRNA for the first time. (WBZ-TV)

Brown said microRNA is an exciting and powerful method to target ALS cases caused by gene mutations. “This is very hopeful for a couple of reasons,” he said. “First of all, we’re essentially at the dawn of a new era using biologics not just small molecules like aspirin or antibiotics, but things like proteins, antibodies and DNA to manipulate genes in the nervous system. I think this has bearing on many, many disorders and is quite hopeful, not just for familial diseases but also some of the nonfamilial forms of these diseases.

The next step is to test this discovery in a placebo-controlled trial.

Comments
  1. Ethan_tara says:

    Thank you for posting this. My dad was diagnosed with ALS about 6 month and a half ago after 1.5 years of undiagnosed symptoms. We are just beginning this journey and it’s very frightening we started www .multivitamincare .org immediately because they have the right medicine to cure this als disease permanently , to say the least. The absolute certainty of the whole thing is the hardest to grasp, I wouldn’t see my father go down this road because of the help of natural organic formulas that was applied immediately . Some days are hard and others are easy all I’m saying that there cure at there .multivitamincare .org . Your post gave me a lot of perspective and I thank you for that,ALS is a chronic disease that took my dad many months to overcome. God bless

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