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Scott%20GrimesScott%20Grimes%2C%20who%20is%20known%20these%20days%20for%20his%20role%20on%20%26%238220%3BE.R.%26%238221%3B%20was%20born%20in%20Lowell.%20Early%20in%20his%20career%2C%20Grimes%20had%20a%20guest%20role%20as%20Alyssa%20Milano%26%238217%3Bs%20boyfriend%20on%20%26%238220%3BWho%26%238217%3Bs%20The%20Boss.%26%238221%3B%20%28Photo%20by%20Frederick%20M.%20Brown%2FGetty%20Images%29%20
Steven%20Wright%20Comedian%20Steven%20Wright%20grew%20up%20in%20Burlington%2C%20Mass.%20%20%28Photo%20by%20Alex%20Wong%2FGetty%20Images%29
Jenny%20Slate%20%20Jenny%20Slate%20became%20an%20overnight%20YouTube%20sensation%2C%20when%20the%20Milton%20native%20let%20the%20F-bomb%20slip%20during%20her%20Saturday%20Night%20Live%20debut%20in%20September%20of%202009.%20%28Photo%20by%20Charles%20Eshelman%2FGetty%20Images%29
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Agnes%20MooreheadAgne%28s%20Moorehead%20%28R%29%2C%20one%20of%20the%20stars%20of%20the%201960%26%238242%3Bs%20television%20show%20%26%238220%3BBewitched%26%238221%3B%20was%20from%20Clinton.%20%28Photo%20credit%3A%20FILES%2FAFP%2FGetty%20Images%29
Carroll%20SpinneyCarroll%20Spinney%2C%20who%20has%20spent%20more%20than%2035%20years%20playing%20Big%20Bird%20and%20Oscar%20the%20Grouch%20on%20%26%238216%3BSesame%20Street%2C%26%238217%3B%20was%20born%20in%20Waltham%20and%20attended%20Acton-Boxboro%20Regional%20High%20School.%20%28Photo%20by%20Noel%20Vasquez%2FGetty%20Images%29
Jeffrey%20DonovanJeffrey%20Donovan%20of%20USA%20network%26%238217%3Bs%20series%20%26%238216%3BBurn%20Notice%26%238217%3B%20was%20born%20in%20Amesbury.%20%20%28Photo%20by%20John%20Parra%2FGetty%20Images%20for%20Custo%20Barcelona%29
Sprague%20GraydenSprague%20Grayden%20of%20%26%238216%3BJericho%26%238217%3B%20and%20%26%238216%3BSix%20Feet%20Under%26%238217%3B%20is%20from%20Manchester%2C%20Mass.%20%20%28Photo%20by%20Alberto%20E.%20Rodriguez%2FGetty%20Images%29
Howie%20LongFootball%20commentator%20Howie%20Long%20was%20born%20in%20Somverville%20and%20attended%20Milford%20High%20School%2C%20before%20going%20on%20to%20be%20an%20NFL%20Hall%20of%20Famer.%20%20%28Photo%20by%20Frank%20Micelotta%2FGetty%20Images%29
Jason%20AlexanderJason%20Alexander%20of%20%26%238220%3BSeinfeld%26%238221%3B%20fame%20attended%20Boston%20University%2C%20but%20left%20school%20before%20graduation.%20%28Photo%20by%20Kevork%20Djansezian%2FGetty%20Images%20for%20VH1%29
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Madeline%20KahnThe%20late%20actress%20Madeline%20Kahn%20of%20%26%238216%3BYoung%20Frankenstein%26%238217%3B%20and%20%26%238216%3BCosby%26%238217%3B%20was%20born%20in%20Boston.%20%28Photo%20credit%3A%20TIMOTHY%20CLARY%2FAFP%2FGetty%20Images%29
John%20O%27HurleyPerhaps%20best%20know%20for%20his%20role%20as%20J.Peterman%20in%20%26%238220%3BSeinfeld%26%238221%3B%2C%20O%26%238217%3BHurley%20lived%20in%20Natick%20for%20a%20time%20during%20childhood.%20%20%28Photo%20by%20Andy%20Kropa%2FGetty%20Images%29
Al%20PacinoAl%20Pacino%20was%20a%20longtime%20member%20of%20David%20Wheeler%26%238217%3Bs%20Theatre%20Company%20of%20Boston%2C%20performing%20on%20Boston%20stages%20in%20the%201970s.%20%28Photo%20by%20Kevin%20Winter%2FGetty%20Images%29
Paget%20BrewsterPaget%20Brewster%20of%20CBS%26%238217%3Bs%20%26%238216%3BCriminal%20Minds%26%238217%3B%20was%20born%20in%20Concord.%20%20%28Photo%20by%20Frazer%20Harrison%2FGetty%20Images%29
Erik%20Per%20SullivanActor%20Erik%20Per%20Sullivan%2C%20best%20known%20as%20little%20brother%20Dewey%20on%20%26%238216%3BMalcom%20in%20the%20Middle%26%238217%3B%2C%20was%20born%20in%20Worcester.%20His%20family%20owns%20a%20restaurant%20in%20Milford.%20%28Photo%20by%20Stephen%20Shugerman%2FGetty%20Images%29
George Carlin
Comedian George Carlin worked at Boston radio station WEZE for three months in the late 1950s. (Photo by Neilson Barnard/Getty Images)
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