BOSTON (CBS) — Red Sox first baseman Mike Napoli will miss Wednesday night’s game against White Sox, but second baseman Dustin Pedroia will return to the lineup and bad leadoff in Chicago.

This will be Pedroia’s first start since Saturday after he missed two games with a sore left wrist. He pinch-ran for Napoli on Tuesday night after the Sox slugger dislocated his finger sliding head-first into second base in the ninth inning.

Pedroia has hit leadoff in 91 games during his career, going 98-for-374 (.262 average) with 29 doubles and 59 runs scored.

READ: Red Sox-White Sox Preview

Boston manager John Farrell said Napoli is considered day-to-day with the injury. With Napoli out, Daniel Nava will get the nod at first.

Here is Boston’s full lineup against Chicago lefty John Danks:

1. Dustin Pedroia, 2B
2. Xander Bogaerts, SS
3. David Ortiz, DH
4. Jonny Gomes, RF
5. Grady Sizemore, LF
6. A.J. Pierzynski, C
7. Daniel Nava, 1B
8. Ryan Roberts, 3B
9. Jackie Bradley Jr., CF
— Clay Buchholz, P



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