Andrew Hatch threw for three touchdowns and Harvard won its season opener, 34-6 over Holy Cross on Saturday night.
Hatch was 20-for-25 passing for 276 yards as the Crimson won for the 11th time in the last 14 games against the Crusaders (1-2).
Hatch threw a 26-yard touchdown pass to Marco Iannuzzi in the second quarter before hooking up with Chris Lorditch on an 8-yard score in the third.
Hatch and Lorditch then got together one more time to cap the Crimson scoring and go up 34-0 on a 43-yard touchdown with 7:13 left in the game.
Harvard kept control of possession, while the Crusaders could not, converting 7 of 12 first downs compared to 5 of 13, and keeping the ball seven minutes longer.
Holy Cross ended the shutout bid on a 15-yard pass from Kevin Watson to Freddie Santana with 1 minute to go.